As Biotron more than doubles on promising COVID results, which other ASX stocks are working on treatments?

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One of the few bright spots in ASX Covid news in the past week, amidst the emergence of the Omicron strain, has been Biotron (ASX:BIT).

The small cap biotech stock has been listed for over 20 years and has had a turbulent history, rising tenfold in 2018 after its BIT225 compound showed potential to fight HIV.

But since the emergance of the COVID-19 pandemic it has sought to develop a treatment against the virus.

And last week it announced the results of a pre-clinical study which showed BIT225 was effective albeit in mice.

The company told shareholders it was keen to proceed the drug into human clinical trials and they responded by more than doubling its share price.

Biotron’s boss Michelle Miller confirmed the plans with Stockhead, noting even with the emergence of COVID-19 treatments – such as the Pfizer and Merck pills – there might be a place for her company.

“It’s a good outcome and offers hope to a lot of people,” she said.

“The FDA are saying we need an arsenal of drugs.

“The vaccines are terrific but it’s not enough unfortunately – there are people even if fully vaccinated that are [at risk, being] immune-compromised or can get a breakthrough infection or vaccine deosn’t take as well.

“I think we are in an exciting spot at the moment.

“We’re in the process of talking to our US experts scoping out the process through the FDA’s Coronavirus Treatment Acceleration Program to really fast-track COVID treatments into the clinic.

“And they want things just like this, tablets or capsules that are direct anti-virals that can be quickly moved, so we’ll get a better understanding of what that’s going to entail.”

 

Other ASX stocks working on COVID treatments

One of the larger ASX stocks trying to prove a COVID-19 treatment is Mesoblast (ASX:MSB).

After its share price spiked throughout much of 2020 as it advanced one of its stem cell infusions (remestemcel-L) into the clinics, it crashed at the end of the year after a setback to that trial and has not recovered.

Yet the company is persisting with remestemcel-L. The FDA recently advised the company that if an additional study in COVID-19 showed positive outcomes, it might be enough to support an emergency use authorisation (EUA).

Among small caps, another company to attract attention recently is Immuron (ASX:IMC), which has completed early stage studies that have shown promising signs.

The list includes a couple of ASX stocks in the medical cannabis space – namely Incannex Healthcare (ASX:IHL) and MGC Pharmaceuticals (ASX:MXC).

Others include Recce Pharmaceuticals (ASX:RCE), Noxopharm (ASX:NOX), Dimerix (ASX:DXB) and Cynata Therapeutics (ASX:CYP).

Many of these companies have specifically targeted acute respiratory distress syndrome (ARDS), one of the major complications and causes of death from COVID-19.

The terrifying inflammatory response leaves patients struggling to breathe as their lungs fill with fluid.

 

Which ASX stocks are the most advanced in their fight against COVID?

Of all these companies, Incannex (ASX:IHL) has had the most positive moves with its ASX shares gaining over 250% in 12 months.

Admittedly much of this has been from progress with its other clinical programs, including against Generalised Anxiety Disorder and concussion.

Dimerix is one of the more advanced, seeking regulatory and ethics approval for a Phase III trial of its DMX-200 drug to be run across Australia and India.

At Stockhead, we tell it like it is. While Incannex, MXC Pharmaceuticals and Dimerix are Stockhead advertisers, they did not sponsor this article. 

The post As Biotron more than doubles on promising COVID results, which other ASX stocks are working on treatments? appeared first on Stockhead.

Weed Week: Cannabis advent calendars and US Republicans introduce weed bill for veterans

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Instead of a chocolate advent calendar this year, Californians can get their hands on a cannabis calendar with edibles, prerolls, grams of flower and four days of cannabis accessories.

“We’ve seen the success of unique advent calendars in other industries,” MonthLeaf president and CEO Bryanne Vincent said.

“This was a way that we could provide our customers with a fun and engaging gift that they can enjoy for an entire month.”

And it might not be long until the calendars are available in the rest of the states, with a new Republican bill soon to be introduced in Congress to legalise and tax cannabis.

The House Veterans’ Affairs Committee has already approved a bill requiring the Department of Veterans Affairs to conduct clinical trials on the medical benefits of marijuana for military veterans with PTSD and chronic pain.

A ‘National Defence Authorization Act amendment’ has been filed that would federally legalise medical marijuana for military veterans – and would allow Department of Veterans Affairs doctors to issue cannabis recommendations and require the department to research marijuana’s therapeutic potential to reduce pain and opioid misuse.

Even Malaysia has made moves to legalise weed, sort of.

The country will allow the import and use of cannabis for medicinal purposes with sellers having sufficient scientific evidence to use cannabis for medicinal purposes able to apply for their product to be evaluated by the Drug Control Authority in order for it to be marketed in Malaysia.
 

Tassie player solidifies Southern Hemisphere position 

On our side of the pond, private company Extractas Bioscience (formerly Tas Alkaloids) has signed a three-year partnership deal with Victorian-based manufacturing company Ensign Laboratories to substantially increase its medicinal cannabis formulation capacities.

In 2019, Extractas constructed a purpose-built, medicinal cannabis cultivation, extraction, formulation and manufacturing facility – which will now produce more than 30,000 bottles per week of finished products under GMP conditions.

“In combination with our extraction capacity of 90 tonnes of biomass/annum we believe that this makes us the GMP* medicinal cannabis manufacturer of choice with one of the largest production capabilities in the Southern Hemisphere,” Extractas executive general manager medicinal cannabis Dr Amy Choi said.

Plus, the company will be the preferred supplier of medicinal cannabis Active Pharmaceutical Ingredients (APIs) to Ensign.

 

ASX Winners

CodeNamePrice%SixMth%Mth%WkMarket Cap
MDCMedlab Clinical Ltd0.18501919 $ 63,302,499.14
CPHCreso Pharma Ltd0.15-213015 $ 174,946,768.37
IHLIncannex Healthcare0.525725413 $ 670,733,041.67
EMDEmyria Limited0.32455212 $ 48,508,229.39
CAUCronos Australia0.187196 $ 8,023,125.00
EXLElixinol Wellness0.096-38-35 $ 30,959,295.25
ZLDZelira Therapeutics0.04-2635 $ 52,325,497.32
MXCMgc Pharmaceuticals0.049-20-164 $ 117,800,696.90
AGHAlthea Group0.275-3364 $ 79,748,610.50
LV1Live Verdure Ltd0.42581134 $ 17,740,248.00
CANCann Group Ltd0.3-3933 $ 104,656,350.90
WOAWide Open Agricultur0.775-553 $ 76,349,990.64
BOTBotanix Pharma Ltd0.061-25-92 $ 60,334,808.59
AVEAvecho Biotech Ltd0.017-6-80 $ 31,213,980.94
IRXInhalerx Limited0.1-500 $ 16,172,827.87
RGIRoto-Gro Intl Ltd0.028-38-70 $ 9,592,598.32
MRGMurray River Grp0.245400 $ 10,808,210.04
SCUStemcell United Ltd0.014-2200 $ 14,606,489.21
YPBYPB Group Ltd0.0030-250 $ 11,861,822.86
ECSECS Botanics Holding0.034-19-130 $ 38,682,543.03
EN1Engage:Bdr Limited0.003-4000 $ 9,143,993.57
AC8Auscann Grp Hlgs Ltd0.097-228-3 $ 44,054,711.00
NTINeurotech Intl0.063719-3 $ 45,293,243.19
PALPalla Pharma Ltd0.345-225-4 $ 55,050,475.42
LGPLittle Green Pharma0.68521-5 $ 122,787,256.05
BODBOD Australia0.26-30-7-5 $ 27,514,219.20
MMJMMJ Group Hlds Ltd0.066-34-10-6 $ 15,406,917.00
IDTIDT Australia Ltd0.4742-25-6 $ 107,937,076.50
WFLWellfully Limited0.09477-35-6 $ 23,090,505.47
ALAArovella Therapeutic0.0393-15-7 $ 21,156,079.38
EOFEcofibre Limited0.735-18-15-8 $ 265,225,224.08
DTZDotz Nano Ltd0.405251-10 $ 171,224,001.56
EPNEpsilon Healthcare0.1125-382-10 $ 22,161,299.14
ROORoots Sustainable0.009-440-10 $ 5,304,386.49
CGBCann Global Limited0.0035-50-13-13 $ 22,174,203.75
RNORhinomed Ltd0.2556-19-14 $ 68,528,465.64
EVEEVE Investments Ltd0.004-330-20 $ 15,372,567.56
TSNThe Sust Nutri Grp0.2-62-32-20 $ 20,392,340.85

 

Leader of the pot stocks was Medlab Clinical (ASX:MDC), up 19% after the US patent office granted patent protection for its NanoCell technology which creates water-soluble nanoparticles that optimise medicinal spray delivery to the lungs.

It’s ideal for people who have difficulties swallowing, fear needles, or experience gastrointestinal complication which can limit absorption.

Plus, the company received AusIndustry Advanced Overseas Finding Approval – Australian Federal Government’s R&D Tax Incentive program – for its NanaBis development program.

Total expenditure for NanaBis development in Australia and overseas for the three-year period is expected to be $26,981,176.

Next up was Creso Pharma (ASX:CPH) which rose 15% off the back of its subsidiary Halucenex’s key psychedelic ingredient passing crucial testing, and progressing towards Phase II clinical trials to test its efficacy on treatment resistant Post Traumatic Stress Disorder.

The company also released its September quarterly which detailed purchase orders secured in Poland for its animal health products and the launching of a new ecommerce platform for new human health products in Switzerland – and the completion and registration of import procedures in Uruguay as a launching off point in Latin America.

Creso is also planning to pursue a NASDAQ dual listing.

Up 13% was Incannex (ASX:IHL), with a psilocybin treatment for generalised anxiety disorder that has received positive feedback from US health regulators following the submission of its pre-investigational new drug application.

The company has also received ethics approval to commence trials at Monash University.

 

The post Weed Week: Cannabis advent calendars and US Republicans introduce weed bill for veterans appeared first on Stockhead.

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